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DeCS
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Descriptor English:
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Antidepressive Agents, Tricyclic
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Descriptor Spanish:
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Antidepresivos Tricíclicos
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Descriptor Portuguese:
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Antidepressivos Tricíclicos
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Synonyms English:
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Agents, Tricyclic Antidepressive
Antidepressant Drugs, Tricyclic
Antidepressants, Tricyclic
Drugs, Tricyclic Antidepressant
Tricyclic Antidepressant Drugs
Tricyclic Antidepressants
Tricyclic Antidepressive Agents
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Tree Number:
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D27.505.954.427.700.122.055
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Definition English:
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Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. |
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History Note English:
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75
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Allowable Qualifiers English:
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Record Number:
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936
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Unique Identifier:
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D000929
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Occurrence in VHL:
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Similar:
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DeCS
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